IL-1β and IL-8 influence on cytoprotective mechanisms in liver tissue in morbid obesity patients with comorbidities
Obesity is a global health problem. Non-alcoholic fatty liver disease (NAFLD) in obese patients is 62—93 %, in type 2 diabetes is prevalent and reaches 55.5 %. The development of chronic subclinical inflammation in obesity contributes to the development of oxidative stress and mitochondrial dysfunction, which underlie the pathogenesis of obesity-associated diseases, ...